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EnginePart report

2006 Ford E-450 Engine Problems

Complaints
4about this part
Share
20%of 20 total for the year
Median mileage
44,000miles
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 4 complaints about the engine of the 2006 Ford E-450, 20% of the 20 complaints for this model year. Where a mileage was given, the median is 44,000 miles.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“Pulled up to stop sign. When making right turn, onto interstate frontage road, throttle quit working, wrench ligh and check engine light came on. Coasted to side of road. Vehicle had to be towed in to Ford dealer. Was told electronic throttle control shut down vehicle, and throttle body would have to be replaced. Had it happened another minute latter it would have failed in the middle of an interstate highway.”

NHTSA complaint #10893869, filed 2016-08, 14,377 miles

“Engine loss of power. Multiple times over the years requiring repairs that never resolved the issue. Ambulance service ended up having to pull from service because of frequency.”

NHTSA complaint #10640604, filed 2014-10, 24,000 miles

“Vehicle was started in garage, backed vehicle up and there was a loud explosion type noise. Mechanic said # 8 plug blew out causing major motor damage.”

NHTSA complaint #10475677, filed 2012-09, 129,855 miles

“The contact owns a 2006 Ford E-450. The contact stated while driving 15 MPH there was a high-pressure oil leak. There were no warning lights illuminated. The vehicle was taken to an independent mechanic who diagnosed the failure to be high-pressure oil leak and EGR failure. The vehicle was repaired; however, failure reoccurred. The manufacturer was notified of the failure. The approximate failure mileage was 64,000.”

NHTSA complaint #11463475, filed 2022-05, 64,000 miles

Engine: other model years

YearComplaintsShare of year
2022215%
2021622%
2017218%
201616%
2015117%
2011114%
2008117%
200718%
2006420%
200539%
2002215%
200012%
199923%

Other parts of the 2006 Ford E-450

Engine cooling
7 complaints
Electrical system
3 complaints
Fuel system
3 complaints
Brakes
2 complaints
Other or unknown
2 complaints
Suspension
2 complaints
Tires
1 complaints

← All problems reported for the 2006 Ford E-450

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 28, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology