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Transmission and drivetrainPart report

2006 Mercedes-Benz CLS500 Transmission and drivetrain Problems

Complaints
4about this part
Share
6%of 62 total for the year
Median mileage
82,650miles
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 4 complaints about the transmission and drivetrain of the 2006 Mercedes-Benz CLS500, 6% of the 62 complaints for this model year. Where a mileage was given, the median is 82,650 miles.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“Brakes keep going out. Brake pedal going to the floor. Esp light comes on and car throttling to a slow creep even on the highway. Extremely dangerous for me and my wife and child.”

NHTSA complaint #11342610, filed 2020-07, 170,000 miles

“The contact owns a 2006 mercedes benz CLS500. While driving at any speed, the engine stalls. The vehicle loses all power, including braking and power steering. The vehicle glided down into a curb due to the failure. When shifted into park, the vehicle restarts normally. The vehicle was taken to the dealer, but they could not repair the failure. Other electrical issues were discovered, but not the cause of the stalling failure. The vehicle also has transmission failure, in whcih the contact believes is the cause of the stalling. The failure mileage was 34,400.”

NHTSA complaint #10270109, filed 2009-05, 34,400 miles

“The contact owns a 2006 mercedes benz CLS500. On october 7, 2006, the contact took his vehicle to the dealer because the transmission was slipping. He has gone to the dealer six different times for this failure in addition to the front end of the vehicle pulling to the left and right, the vehicle lurching when driving between 40 and 50 MPH, and to retrieve a keyless remote. In regards to the transmission slipping, the contact was told that it was a software failure and the dealer did not have the software to perform the repair. The engine size was unknown. …”

NHTSA complaint #10191306, filed 2007-05, 13,674 miles

Related service bulletins

Transmission and drivetrain: other model years

YearComplaintsShare of year
200646%

Other parts of the 2006 Mercedes-Benz CLS500

Brakes
23 complaints
Fuel system
23 complaints
Air bags
5 complaints
Wheels
4 complaints
Electrical system
3 complaints
Electronic stability control
3 complaints
Vehicle speed control
3 complaints
Engine
2 complaints
Tires
2 complaints
Seats
1 complaints
Suspension
1 complaints
Visibility (wipers, defrost, mirrors)
1 complaints

← All problems reported for the 2006 Mercedes-Benz CLS500

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology