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Transmission and drivetrainPart report

2006 Mercedes-Benz E500 Transmission and drivetrain Problems

Complaints
2about this part
Share
4%of 50 total for the year
Median mileage
46,010miles
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 2 complaints about the transmission and drivetrain of the 2006 Mercedes-Benz E500, 4% of the 50 complaints for this model year. Where a mileage was given, the median is 46,010 miles.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“This has actually happened 2x already-I was stationary at a light and when I went to accelerate the car stalled and would not start back up. There where many cars behind me and my car would not move. I turned car off and then it finally restarted and I was able to pull over on the side of the road . I was terrified. The second time the car was actually moving and then just died in the middle of the intersection. I took it to the dealer both times and since nothing came up on my dash they could not find out what was wrong. I am terrified this will happen again without a good outcome next time. …”

NHTSA complaint #11299230, filed 2020-01, 92,000 miles

Related service bulletins

Transmission and drivetrain: other model years

YearComplaintsShare of year
200624%
200564%
200475%
2003108%

Other parts of the 2006 Mercedes-Benz E500

Fuel system
29 complaints
Air bags
4 complaints
Wheels
4 complaints
Brakes
3 complaints
Electrical system
3 complaints
Suspension
3 complaints
Steering
2 complaints
Visibility (wipers, defrost, mirrors)
2 complaints
Electronic stability control
1 complaints
Engine
1 complaints
Other or unknown
1 complaints
Seat belts
1 complaints

← All problems reported for the 2006 Mercedes-Benz E500

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology