2006 Mercedes-Benz E350 Equipment Problems
- Complaints
- 2about this part
- Share
- 1%of 400 total for the year
- Median mileage
- 40,000miles
- Trend
- Not enough dataFewer than 15 complaints, too few for a reliable trend.
NHTSA recorded 2 complaints about the equipment of the 2006 Mercedes-Benz E350, 1% of the 400 complaints for this model year. Where a mileage was given, the median is 40,000 miles.
Fewer than 15 complaints name this part, so treat the figures as a rough indication only.
Example complaints
Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.
“I own a 2006 mercedes e-series with 47,000 miles. I have noticed a fuel smell when the car is in the garage after refilling the tank. The problem was recently diagnosed as a faulty fuel tan seal. The dealer has indicated this is a dangerous condition and the car should not be driven. The estimated repair cost is over $600. In researching this on the internet I find this is a common dangerous problem but there has not been a recall. I also find that in instances where the seal has been replaced, the problem recurs a short time later and it is related to the entire mechanism, not just the seal. …”
NHTSA complaint #10533355, filed 2013-08, 40,000 milesRelated service bulletins
- 10135628Oct 14, 2014iPhone mobile phone: Various complaints after software update to iOS8
- 10167525Mar 3, 2014Apple products (iPhone or iPod) are not charged via the serial USB interface of the COMAND Online control unit (A40/3) in the stowage compartment of the center console.
- 10166975Feb 11, 2014This Customer 1 Action has been initiated because certain mbrace subscribers were recently contacted by mbrace informing them that they need to have an i-button call performed to…
- 10166976Feb 3, 2014Message in instrument cluster "DISTRONIC PLUSCurrently Unavailable - See Owner's Manual"
Equipment: other model years
Other parts of the 2006 Mercedes-Benz E350
219 complaintsBrakes
54 complaintsEngine
50 complaintsTransmission and drivetrain
37 complaintsEngine cooling
22 complaintsElectrical system
19 complaintsAir bags
13 complaintsOther or unknown
11 complaintsVisibility (wipers, defrost, mirrors)
8 complaintsVehicle speed control
7 complaintsSteering
6 complaintsElectronic stability control
5 complaints
← All problems reported for the 2006 Mercedes-Benz E350
About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Nov 1, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.
To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology