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Transmission and drivetrainPart report

2022 Mercedes-Benz GLS 450 4MATIC Transmission and drivetrain Problems

Complaints
4about this part
Share
24%of 17 total for the year
Median mileage
—not reported
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 4 complaints about the transmission and drivetrain of the 2022 Mercedes-Benz GLS 450 4MATIC, 24% of the 17 complaints for this model year. 2 of these say a crash was involved, according to the filers. 1 recall campaign on record is filed under a similar system.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“While backing out of steep driveway, the car computer screen blinked saying updating then screen went blank, lost power, I could not brake. We have a row of trees at the back of our driveway that stopped the car ( with damage) or else we would have rolled into our neighbors basement all. Tree limbs poked a hole in bumper, cracked left tail light, and damaged the back hatch. Mercedes is saying User fault. I have been driving for 45 years without a ticket, wreck or causing an accident, and I am not a liar. …”

NHTSA complaint #11609145, filed 2024-08

“Vehicle lost power while driving on a busy freeway and came to a complete stop and would not restart resulting in it being struck by a vehicle in the rear. More information available in the collision center pre estimate scan and full estimate.”

NHTSA complaint #11632849, filed 2024-12

“The vehicle suffered a total internal transfer case mechanical failure at 22,909 miles, which was documented during a factory-scheduled Service B check. The dealership attempted a fluid flush, which immediately resulted in an active 4MATIC system failure warning on the dashboard. Complete mechanical failure of this 4MATIC component causes extreme drivetrain binding and wheel hopping during low-speed maneuvers, presenting a major vehicle control hazard and a high risk of sudden loss of propulsion while driving on public roads.”

NHTSA complaint #11768362, filed 2026-10

Related recalls

Related service bulletins

Transmission and drivetrain: other model years

YearComplaintsShare of year
202417%
2022424%

Other parts of the 2022 Mercedes-Benz GLS 450 4MATIC

Other or unknown
6 complaintsElectrical system
4 complaintsForward collision avoidance
4 complaintsEngine
3 complaintsVehicle speed control
3 complaintsBrakes
2 complaintsFuel system
2 complaintsLane departure
1 complaintsVisibility (wipers, defrost, mirrors)
1 complaintsWheels
1 complaints

← All problems reported for the 2022 Mercedes-Benz GLS 450 4MATIC

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Nov 1, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology