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Mercedes-Benz GLS580Model year report

2021 Mercedes-Benz GLS580 Problems

Complaints
5filed with NHTSA
Median mileage
43,000miles, 2 complaints with mileage
Recalls
11campaigns on record
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.
NHTSA crash rating
—no overall rating published
EPA fuel economy
18 mpgcombined, 4.0L 8-cyl · hybrid 4WD · 16 city / 21 hwy

Sources: NHTSA records for the 2021 Mercedes-Benz GLS580 (complaints, recalls, investigations), EPA fuel economy. Report an error

NHTSA recorded 5 consumer complaints for the 2021 Mercedes-Benz GLS580. The part named most often is electrical system, with 2 complaints (40% of the total), followed by engine (2) and air bags (1). 2 of the complaints include a mileage, and 50% of those were filed for vehicles with under 50,000 miles; the median is 43,000 miles. Of all complaints, 1 involved a crash, 2 an injury, according to the filers. NHTSA lists 11 recall campaigns and 268 technical service bulletins for this model year. Electrical system complaints overlap with 4 recall campaigns covering the interior/under dash and 129 technical service bulletins filed under the same part. Engine complaints overlap with 13 technical service bulletins filed under the same part.

This model year has fewer than 25 complaints on record, so the numbers below can change a lot with a few new reports.

Which parts are reported most

Complaints can name more than one part, so the counts add up to more than the total. Select a part to see its complaints, recalls and bulletins.

Example complaints

Electrical system: “Delivered an unfinished or car with a broken part,Seat Problem not locking properly, Electrical Problem, Engine Light Came on, ESP warning, Suspension Problem, Battery Problem, Steering Jerking, Mirror Problem which they said Mercedes Benz aware of it, some sort of sound, car getting hot excessively.”

NHTSA complaint #11574364, filed 2024-02

Engine: “The vehicle suffered a sudden, catastrophic 48V mild-hybrid electrical power supply breakdown and complete system failure while traveling at highway speeds during a cross-country move. The sudden failure forced an emergency lane change into an isolation zone just off the highway. The sudden failure left the cabin completely powerless with no operational safety systems, hazard lights, or air conditioning in extreme 100+ degree heat. …”

NHTSA complaint #11753406, filed 2026-07

Air bags: “The contact owns a 2021 Mercedes Benz GL550. The contact stated that while driving 30 -35 mph an unknown vehicle crossed her path, the driver depressed the brake pedal but was unable to stop before colliding with a vehicle. The steering wheel air bag split open and deployed. The contact sustained injuries, the inside of her right arm was cut. The air bags on the floor deployed and contact sustained severe burns on her shin medical attention was provided. The contact stated she still has an open wound. The distance warning indicator light was illuminated. There was no reported fire. …”

NHTSA complaint #11444154, filed 2021-12, 3,000 miles

Fuel system: “The contact owns a 2021 Mercedes-Benz GLS580. The contact stated that after entering the vehicle, the contact became aware of an abnormally strong fuel odor inside the vehicle. There was no warning light illuminated. The vehicle was taken to two independent mechanics who referred the contact to the local dealer for assistance. The local dealer was contacted, but the vehicle was not diagnosed or repaired. The manufacturer was not contacted. The failure mileage was approximately 83,000.”

NHTSA complaint #11701200, filed 2025-11, 83,000 miles

Mileage when problems were reported

50% of the 2 complaints with a mileage were filed for vehicles with under 50,000 miles; the middle half falls between 3,000 and 83,000 miles.

50%0–100%10–250%25–500%50–7550%75–1000%100–1500%150+
Share of complaints by mileage when the problem was reported, in thousands of miles (2 complaints with mileage). Red bars: under 50,000 miles. Bucket widths differ. Median: 43,000 miles.

Complaints by year filed

Fewer than 15 complaints, too few for a reliable trend.

2021120221202412025120261
Complaints by year the complaint was filed with NHTSA. Red bars: the last 3 full calendar years used for the trend. The current year (2026) is partial.

Fuel economy and running cost

EPA ratings for each 2021 Mercedes-Benz GLS580 version. Annual fuel cost is the EPA's estimate at its current fuel prices for 15,000 miles a year (55% city driving).

VersionEngineTransmissionCityHwyComb.Fuel / yr
GLS580 4matic 4WD4.0L 8-cyl · hybrid9-speed automatic162118$4,550

Source: U.S. EPA and Department of Energy, fueleconomy.gov. Ratings are for comparing vehicles; real-world mileage varies with driving and conditions.

Recalls and investigations

See all 11 recalls for the 2021 Mercedes-Benz GLS580 → · Check a VIN at nhtsa.gov/recalls

Technical service bulletins

TSBs are manufacturer notes to dealers about known repair procedures. They are not recalls and do not by themselves mean a vehicle has a fault. 268 on record; the latest 10 are shown.

See all 268 bulletins →

Other model years of the Mercedes-Benz GLS580

YearComplaintsMedian miRecallsCrash ★MPGScore (50 = typical)Trend
2021543,00011—18—Not enough data

All Mercedes-Benz GLS580 model years

Frequently asked questions

How many NHTSA complaints does the 2021 Mercedes-Benz GLS580 have?

NHTSA recorded 5 consumer complaints for the 2021 Mercedes-Benz GLS580 as of Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

What part of the 2021 Mercedes-Benz GLS580 is reported most often?

Electrical system is named most often, in 2 complaints (40% of the total), followed by engine with 2.

Has the 2021 Mercedes-Benz GLS580 been recalled?

NHTSA lists 11 recall campaigns for this model year. To check a specific vehicle, enter its VIN at nhtsa.gov/recalls.

What gas mileage does the 2021 Mercedes-Benz GLS580 get?

The EPA rates the 2021 Mercedes-Benz GLS580 (GLS580 4matic, 4.0L 8-cyl · hybrid) at 18 mpg combined, 16 city and 21 highway, with an estimated annual fuel cost of $4,550 at 15,000 miles a year. Other engine and drive versions are rated differently.

At what mileage are problems with the 2021 Mercedes-Benz GLS580 reported?

Among the 2 complaints that include a mileage, the median is 43,000 miles and the middle half falls between 3,000 and 83,000 miles; 50% were filed for vehicles with under 50,000 miles.

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate. Fuel economy is from the EPA and DOE (fueleconomy.gov).

Complaint counts come from NHTSA’s public complaint database; we count each complaint once. The source records for this vehicle are on nhtsa.gov. Scores and trends are our own summaries of that data, described in the methodology. This page is not legal, safety or repair advice: for a specific vehicle, check its VIN at nhtsa.gov/recalls and ask a qualified mechanic. See an error? Tell us.