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Transmission and drivetrainPart report

2019 Mercedes-Benz E 450 Transmission and drivetrain Problems

Complaints
4about this part
Share
24%of 17 total for the year
Median mileage
7,200miles
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 4 complaints about the transmission and drivetrain of the 2019 Mercedes-Benz E 450, 24% of the 17 complaints for this model year. Where a mileage was given, the median is 7,200 miles.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“Driving at 75 MPH, car suddenly decelerated to approx 45mph without warning. A triangle with red image of the car's rear appeared on screen. I gradually increased speed back up to 70 MPH and same problem occurred. Car is 2 yrs old with 7200 miles on it. M-b dealership has the car now.”

NHTSA complaint #11387009, filed 2021-01, 7,200 miles

“I was driving about 30 mph and getting on to the highway. Once I got on a beep came on from the car and every single warning light came on the car. Check engine all warnings including emergency brake collision warning the list goes on and on. I immediately got off the highway and once I got to a complete stop the car was barely accelerating. I wasn’t able to shift gears from drive I was stuck in drive. Couldn’t park the car reverse or anything. I had to turn the car off. The car didn’t turn on and then after 5 minutes it turned back on. …”

NHTSA complaint #11668083, filed 2025-06

“The primary failure involved the electrical system and speed control, which posed a significant safety risk to myself and other drivers. The issue first presented itself when I noticed intermittent warning lights and error messages flashing on the dashboard, including indicators for the electronic stability program (ESP), steering assist, and lane tracking features. These malfunctions created erratic driving conditions, including unexpected acceleration delays and inconsistent cruise control behavior. …”

NHTSA complaint #11658594, filed 2025-05

Related service bulletins

Transmission and drivetrain: other model years

YearComplaintsShare of year
2023424%
202219%
2020111%
2019424%

Other parts of the 2019 Mercedes-Benz E 450

Electrical system
5 complaints
Brakes
4 complaints
Engine
4 complaints
Forward collision avoidance
3 complaints
Back-over prevention (rear camera)
2 complaints
Steering
2 complaints
Air bags
1 complaints
Engine cooling
1 complaints
Exterior lighting
1 complaints
Fuel system
1 complaints
Lane departure
1 complaints
Other or unknown
1 complaints

← All problems reported for the 2019 Mercedes-Benz E 450

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology