2022 Mercedes-Benz E 450 Transmission and drivetrain Problems
- Complaints
- 1about this part
- Share
- 9%of 11 total for the year
- Median mileage
- —not reported
- Trend
- Not enough dataFewer than 15 complaints, too few for a reliable trend.
NHTSA recorded 1 complaints about the transmission and drivetrain of the 2022 Mercedes-Benz E 450, 9% of the 11 complaints for this model year.
Fewer than 15 complaints name this part, so treat the figures as a rough indication only.
Example complaints
Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.
“Twice within a year a 48 voltage battery malfunction warning appeared on my dashboard. Then a red warning light appears and I had about 30 seconds to find a safe place to pull over as loss of power causes deceleration of the vehicle . The cause, according to the diagnostic test performed by 2 different Mercedes dealerships, is that a software update is needed. A know of no situation where the machine crashes first then you're told to update its software. …”
NHTSA complaint #11629635, filed 2024-12Related service bulletins
- 11038187Sep 26, 2026Complaint Customer complaints relating to automatic transmission 725.0 (NAG3 Classic /9G‑TRONIC automatic transmission) and 725.1 (NAG3 facelift/9G‑TRONIC automatic transmission…
- 11037616Sep 4, 2026Complaint Customer complaints relating to automatic transmission 725.0 (NAG3 Classic / 9G‑TRONIC automatic transmission) and 725.1 (NAG3 facelift/9G‑TRONIC automatic transmission…
- 11036077Aug 5, 2026Complaint This document is intended as a pre-case diagnostic reference for transmission related concerns. It will also ensure that if a case is necessary, all supporting…
- 11035780Aug 4, 2026Complaint Mercedes-Benz USA is currently experiencing limited availability of transmission fluid specification ATF 236.17 due to a global supply constraint. 236.17 ATF 1L and 5L…
- 11035005Jul 14, 2026Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The noise is heard once in each instance when changing direction of…
- 11033050May 22, 2026Dear Mercedes-Benz USA Dealers, The part numbers listed in the chart below should no longer be installed, and any existing stock must be returned to your facing PDC. The deadline…
- 11032736May 15, 2026The part numbers listed in the chart below should no longer be installed, and any existing stock must be returned to your facing PDC. The deadline for all dealer returns is no…
- 11028834Feb 13, 2026Complaint Check engine light on with the following fault is current in the VGS Control Unit: P084300 Oil pressure sensor 'A' has a short circuit to positive stored in VGS control…
- 11028270Feb 3, 2026Complaint Only vehicles with a variable transfer case are affected. This can be identified through control unit N45 or N15/7 in the quick test. When accelerating with light load…
- 11026833Dec 20, 2025Complaint (Original LI document #: LI27.35-P-079039) Clicking noises from the electro-hydraulic control unit (EHS) when the vehicle is stationary and ECO Start/Stop is active…
Transmission and drivetrain: other model years
Other parts of the 2022 Mercedes-Benz E 450
4 complaintsFuel system
3 complaintsBrakes
2 complaintsWheels
2 complaintsEngine
1 complaintsForward collision avoidance
1 complaintsSteering
1 complaintsBody and structure
1 complaints
← All problems reported for the 2022 Mercedes-Benz E 450
About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Nov 1, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.
To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology