2016 Mercedes-Benz E350 Transmission and drivetrain Problems
- Complaints
- 5about this part
- Share
- 10%of 51 total for the year
- Median mileage
- 84,000miles
- Trend
- Not enough dataFewer than 15 complaints, too few for a reliable trend.
NHTSA recorded 5 complaints about the transmission and drivetrain of the 2016 Mercedes-Benz E350, 10% of the 51 complaints for this model year. Where a mileage was given, the median is 84,000 miles.
Fewer than 15 complaints name this part, so treat the figures as a rough indication only.
Example complaints
Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.
“When I try to put the vehicle in park the car is stuck in drive or reverse. If the car is in reverse or if the vehicle is in drive and you use the gear selector to put the vehicle in park or change and gear the vehicle does not change the gear. I bought this vehicle certified preowned from Mercedes-Benz dealership in july 2019 the vehicle has less than 4000 miles on it since I bought it certified and this issue has occurred. This is a safety issue which could have injury and or death. …”
NHTSA complaint #11394574, filed 2021-02, 39,000 miles“I have had 2 mb e-350 engine failures within 13 months. Both were camshaft sensor issues. When I researched this issue I see that mb had a know defect in or about 2009 with these engines. I believe that it remains unresolved today. The chances of one person having 2 vehicles with the same defect causing approximately $9,000 each in losses is close to the chances of being attacked by a black bear and a polar bear in the same day. I think that there is a hidden defect that mb is not recognizing. It is costing consumers thousands of $$ in repairs due solely to this defect and should be a mb cost.”
NHTSA complaint #10983849, filed 2017-05, 84,000 miles“When accelerating from a stop, the 722.9 7g-tronic automatic transmission sometimes get stuck in 1st gear. The engine speed almost instantaneously exceeds 5000 RPM. The car must be immediately driven off the road, the engine turned off and then restarted. The transmission will then shift properly until the next time it fails which could be at almost any time. This is a very common complaint which mercedes benz has known about for years. Only mercedes benz will repair the problem since they will not allow 3rd parties access to the repair parts. Their cost to repair is in excess of $2000. …”
NHTSA complaint #10954937, filed 2017-02, 138,000 miles“The contact owns a 2016 Mercedes-Benz E350. The contact stated while shifting between the lower gears, the vehicle would shift roughly resulting in the vehicle jerking while driving. The contact stated no warning light was illuminated. The vehicle was taken to a local dealer where it was diagnosed with needing the transmission replaced. The vehicle was not repaired. The manufacturer was informed of the failure and informed the contact that the VIN was not under recall. The contact was transferred to the NHTSA for assistance. The failure mileage was approximately 107,000.”
NHTSA complaint #11448342, filed 2022-01, 107,000 miles“The contact owns a 2016 mercedes benz E350. While driving approximately 75 MPH, the collision assist inoperative warning indicator displayed on the instrument panel and the cruise control warning indicator illuminated. The accelerator pedal was depressed, but the vehicle did not respond. The vehicle would not down shift. The contact lost control of the vehicle. The vehicle was taken to a dealer for diagnostic testing. The vehicle was unable to be diagnosed and the software was reset. The failure recurred. The manufacturer was notified of the failure. The approximate failure mileage was 4,800. …”
NHTSA complaint #10816678, filed 2015-12, 4,800 milesRelated service bulletins
- 11035005Jul 14, 2026Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The noise is heard once in each instance when changing direction of…
- 11025648Nov 15, 2025Complaint Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The clunk is heard once when changing from forward to reverse…
- 11023193Sep 17, 2025Complaint Transmission control unit Y3/8n4 (fully integrated transmission control unit (VGS)) not listed in quick test and/or no communication possible with VGS. Cause…
- 11019018May 21, 2025Complaint Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The clunk is heard once when changing from forward to reverse…
- 11013994Feb 7, 2025Mercedes-Benz AG, the manufacturer of Mercedes-Benz vehicles, has determined that on certain MY 2016-2019 E-Class (213 and 238 platform) and S-Class (217 and 222 platform)…
- 11013298Jan 16, 2025Complaint Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The clunk is heard once when changing from forward to reverse…
- 11013332Jan 15, 2025Complaint Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The noise is heard once in each instance when changing…
- 11010818Nov 20, 2024Complaint Transmission control unit Y3/8n4 (fully integrated transmission control unit (VGS)) not listed in quick test and/or no communication possible with VGS. Cause…
- 11008873Oct 1, 2024Complaint Tension-releasing impact of the propeller shaft with the force-free in D "KID" function, after vehicle has stopped. Cause The tension-releasing jolt in the drivetrain…
- 10179949Aug 24, 2020Shifting complaints and transmission fault codes in vehicles with transmission 725.0
Transmission and drivetrain: other model years
| Year | Complaints | Share of year |
|---|---|---|
| 2022 | 1 | 11% |
| 2021 | 3 | 23% |
| 2020 | 1 | 13% |
| 2016 | 5 | 10% |
| 2015 | 1 | 3% |
| 2014 | 15 | 5% |
| 2013 | 7 | 4% |
| 2012 | 10 | 5% |
| 2011 | 6 | 3% |
| 2010 | 14 | 8% |
| 2009 | 2 | 3% |
| 2008 | 5 | 3% |
| 2007 | 21 | 6% |
| 2006 | 37 | 9% |
| 2003 | 1 | 14% |
Other parts of the 2016 Mercedes-Benz E350
9 complaintsOther or unknown
8 complaintsBody and structure
7 complaintsVisibility (wipers, defrost, mirrors)
7 complaintsAir bags
6 complaintsEngine
5 complaintsSteering
5 complaintsVehicle speed control
5 complaintsFuel system
4 complaintsBrakes
3 complaintsExterior lighting
2 complaintsForward collision avoidance
2 complaints
← All problems reported for the 2016 Mercedes-Benz E350
About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Nov 1, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.
To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology