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EnginePart report

2016 Mercedes-Benz E350 Engine Problems

Complaints
5about this part
Share
10%of 51 total for the year
Median mileage
41,500miles
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 5 complaints about the engine of the 2016 Mercedes-Benz E350, 10% of the 51 complaints for this model year. Where a mileage was given, the median is 41,500 miles. 1 a fire, according to the filers.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“Since May 2024, I had taken my car in for repairs at 3 different shops for same exact issue diagnosed as leak from air intake system. It has been repaired 7 times since it first occurred in May 2024, and unfortunately it is still not resolved. This is a potential danger to the driver because all of a sudden there will be loud noise from the engine, car will start misfiring and slow down the speed. The previous 3 attempts of repair were made at Mercedes Benz of West Covina. The car is non drivable at the moment.”

NHTSA complaint #11620163, filed 2024-10

“The contact owns a 2016 Mercedes-Benz E350. The contact stated that there was an oil burning odor present inside and outside of the vehicle. The vehicle was taken to the local dealer who diagnosed that the engine drive belts were faulty, and corrosion was present on the motor mounts. The vehicle was not yet repaired. In addition, the HVAC system was faulty causing mold and mildew to build up inside the vehicle. The manufacturer was not yet notified. The failure mileage was 55,000.”

NHTSA complaint #11440184, filed 2021-11, 55,000 miles

“Re-Seal Upper Timing Covers of the cylinder head timing covers are seeping. 2016 E350 has less thank 19k on it. The fluids can potentially leak onto the roads causing a hazard, it is also a fire hazard, as well as an environmental issue. This was identified by Revolution Mercedes in Decatur, GA. After reading some forums, I have seen where others are having similar issues and believe this should be addressed.”

NHTSA complaint #11435866, filed 2021-10

“Dealership stated on 6/4/24 extensive rust and perforations on rear vehicle sub frame that can cause risk to driver of accident or injury. MBUSA is offering to replace sub frame part # 212 350 38 05. However dealership advised MBUSA is not offering to replace corroded brake lines or brake fluid exchange, and would need to come out of pocket. MBUSA failed to notify me of safety defect. Vehicle was purchased from MB of Arlington, VA in 4/2019 however dealership sold vehicle that is dangerous to drive. …”

NHTSA complaint #11592509, filed 2024-06

“The contact owned a 2016 Mercedes-Benz E350. While driving 5 MPH, a strong odor of fuel entered the cabin of the vehicle through the air conditioning system. Directly afterwards, the contact heard three explosive noises coming from the engine compartment. The contact pulled the vehicle over, opened the hood, and noticed flames under the hood. A police report was filed. The fire department extinguished the fire. There were no injuries. The vehicle was destroyed. Mercedes-benz nationwide in miami, florida and manufacturer were made aware of the fire. The failure mileage was approximately 28,000.”

NHTSA complaint #11064455, filed 2018-01, 28,000 miles

Related service bulletins

Engine: other model years

YearComplaintsShare of year
2021431%
2020338%
2017229%
2016510%
201526%
2014207%
2013159%
2012209%
2011136%
2010158%
200958%
2008138%
2007288%
20065013%

Other parts of the 2016 Mercedes-Benz E350

Electrical system
9 complaints
Other or unknown
8 complaints
Body and structure
7 complaints
Visibility (wipers, defrost, mirrors)
7 complaints
Air bags
6 complaints
Steering
5 complaints
Transmission and drivetrain
5 complaints
Vehicle speed control
5 complaints
Fuel system
4 complaints
Brakes
3 complaints
Exterior lighting
2 complaints
Forward collision avoidance
2 complaints

← All problems reported for the 2016 Mercedes-Benz E350

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology