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Body and structurePart report

2016 Mercedes-Benz E350 Body and structure Problems

Complaints
7about this part
Share
14%of 51 total for the year
Median mileage
55,000miles
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 7 complaints about the body and structure of the 2016 Mercedes-Benz E350, 14% of the 51 complaints for this model year. Where a mileage was given, the median is 55,000 miles.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“Panoramic roof making noise. Upon dealer troubleshooting was informed panoramic roof weld or hardware is affected. Car only has 35000 miles and car was about week past the 5 year manufacture warranty. I was informed dealer would have to replace the panoramic sunroof and cost will be around $8500.00 issue is noticed when car is driven and noise gets louder and frequent with high temp outside.”

NHTSA complaint #11324193, filed 2020-05, 28,000 miles

“The contact owns a 2016 Mercedes-Benz E350. The contact stated that there was an oil burning odor present inside and outside of the vehicle. The vehicle was taken to the local dealer who diagnosed that the engine drive belts were faulty, and corrosion was present on the motor mounts. The vehicle was not yet repaired. In addition, the HVAC system was faulty causing mold and mildew to build up inside the vehicle. The manufacturer was not yet notified. The failure mileage was 55,000.”

NHTSA complaint #11440184, filed 2021-11, 55,000 miles

“The contact owns a 2016 Mercedes-Benz E350. The contact stated that water was leaking inside the vehicle through the seal around the windshield. The contact stated that upon manually pushing the windshield, the windshield was movable. Additionally, the contact stated that there was a windy sound coming through the windshield while driving. The vehicle was taken to Dunaway Glass Repair Company, where the windshield was being replaced. The vehicle was being repaired. The manufacturer was notified of the failure and informed the contact that the VIN was not under recall. …”

NHTSA complaint #11703257, filed 2025-12, 140,000 miles

“Dealership stated on 6/4/24 extensive rust and perforations on rear vehicle sub frame that can cause risk to driver of accident or injury. MBUSA is offering to replace sub frame part # 212 350 38 05. However dealership advised MBUSA is not offering to replace corroded brake lines or brake fluid exchange, and would need to come out of pocket. MBUSA failed to notify me of safety defect. Vehicle was purchased from MB of Arlington, VA in 4/2019 however dealership sold vehicle that is dangerous to drive. …”

NHTSA complaint #11592509, filed 2024-06

“Started developing (April 2021) a rattle in car's roof along with occasional metal popping sound coming from rear of car. Continued to get worse. Then rattle stopped for a while and so did the metal popping sound. Now ( August, 2021)it sounds like there is a bolt loose in the sunroof area and the metal popping sound is really loud and I think coming from roof. Most of the time when car body twist, like going up a slight incline at an angle when entering a parking lot this incredible loud popping sound resonates throughout the entire car body. …”

NHTSA complaint #11428604, filed 2021-08

Related service bulletins

Body and structure: other model years

YearComplaintsShare of year
2017114%
2016714%
2015413%
2014259%
20131811%
201284%
2011157%
2010116%
200935%
200863%
200721%
200651%
200517%

Other parts of the 2016 Mercedes-Benz E350

Electrical system
9 complaints
Other or unknown
8 complaints
Visibility (wipers, defrost, mirrors)
7 complaints
Air bags
6 complaints
Engine
5 complaints
Steering
5 complaints
Transmission and drivetrain
5 complaints
Vehicle speed control
5 complaints
Fuel system
4 complaints
Brakes
3 complaints
Exterior lighting
2 complaints
Forward collision avoidance
2 complaints

← All problems reported for the 2016 Mercedes-Benz E350

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology