2010 Mercedes-Benz E350 Body and structure Problems
- Complaints
- 11about this part
- Share
- 6%of 184 total for the year
- Median mileage
- 36,200miles
- Trend
- Not enough dataFewer than 15 complaints, too few for a reliable trend.
NHTSA recorded 11 complaints about the body and structure of the 2010 Mercedes-Benz E350, 6% of the 184 complaints for this model year. Where a mileage was given, the median is 36,200 miles. 2 of these say a crash was involved, according to the filers.
Fewer than 15 complaints name this part, so treat the figures as a rough indication only.
Example complaints
Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.
“Another car made an illegal u-turn and caused me to t-bone on his passenger side. Front of my car hit his passenger side and dragged his car for about 10 feet. Air bags on my car did not deploy, safety system m-brace in car failed and did not call sos either. Car safety system did not detect the crash at all. Mercedes benz did not detect a crash....updated 09-10-14 the consumer stated she received soft tissue injuries to the neck, shoulders, and back, bruised elbow, and headaches and loud ringing for 10 days caused by the crash. Updated 12/16/2014”
NHTSA complaint #10628111, filed 2014-08, 23,000 miles“Molds and mildew build up in the air condition ducts placing people who are susceptible for infection (people with weak immune system) at risk for fatal infection. The dealer stated that this is a known and common condition for this car because the AC box does not drain the condensed water. This is because the way the car was designed. The dealer recommended turning off the AC for 30 seconds while keeping just the fan on every time before turning off the car to dry up the condensed water on the AC coils, not practical. …”
NHTSA complaint #10615573, filed 2014-07, 36,200 miles“Rear subframe corrosion and failure. Based on my queries this apparently a common issue. I am adding my report to add weight to this common issue. Vehicle is approximately 13 years old, is in good condition, and has not suffered any accidents affecting the rear subframe. Overall only minimal rust or corrosion is found during a visual inspection while on a lift. This vehicle has passed annual inspections as required by Virginia state law. The rear subframe has rusted from the inside. This corrosion was not visible from the outside, which is why it was not found in the annual inspections. …”
NHTSA complaint #11544758, filed 2023-09“The contact owns a 2010 Mercedes- Benz E 350. The contact stated that while driving there was an undetermined abnormal noise detected. The vehicle was taken to an independent mechanic where it was informed the sub frame was corroded The independent dealer was contacted. The vehicle was diagnosed or repaired. The manufacturer was notified electronically however no response was provided. The failure mileage was approximately 171,000.”
NHTSA complaint #11436456, filed 2021-10, 171,000 miles“Per the technician: the rear subframe is rusted out and the lateral strut arm is starting to break away . Because of this issue, the car unknowingly presented a safety risk to occupants and other drivers. A failure of the subframe or connected components could have resulted in a serious accident. Photos are attached. The vehicle is currently available for inspection upon request. There were no warning indicators to this issue. The issue was found only because the car was being serviced for brake pads. …”
NHTSA complaint #11522257, filed 2023-05Related service bulletins
- 11038217Sep 14, 2026Complaint Clanking noise from the area of the speakers in the doors. Cause Under analysis. Remedy To narrow down the cause, first of all remove the door trim. • If the noise…
- 11036101Aug 6, 2026Complaint Clanking noise from the area of the speakers in the doors. Cause Under analysis. Remedy To narrow down the cause, first of all remove the door trim. • If the noise…
- 11033181Jun 2, 2026Complaint The underfloor paneling is loose or sags (picture 1). Cause Mounting clips broken or not correctly engaged. Remedy Replace all mounting clips with collar nuts with…
- 11009122Oct 23, 2024Complaint Washer fluid system leaks Cause Various possible causes: 1. Washer fluid reservoir itself. 2. Seal on washer fluid pump/washer fluid reservoir. 3. Washer fluid pump…
- 10252770Mar 12, 2024As previously reported, to enhance the satisfaction of our customers, avoid further costs of litigation and return focus to its core businesses, Mercedes-Benz USA, LLC (MBUSA)…
- 10235673Apr 28, 2023To enhance the satisfaction of our customers, avoid further costs of litigation and return focus to its core businesses, Mercedes-Benz USA, LLC (MBUSA) has entered into a…
- 10233780Mar 10, 2023Mercedes-Benz USA, LLC (MBUSA) has extended the warranty for the rear subframe on the vehicles listed below, from the original New Vehicle Limited Warranty of 4 years/50,000…
- 10232321Feb 10, 2023Mercedes-Benz USA, LLC (MBUSA) has extended the warranty for the rear subframe on the vehicles listed below, from the original New Vehicle Limited Warranty of 4 years/50,000…
- 10231042Jan 25, 2023To enhance the satisfaction of our customers, avoid further costs of litigation and return focus to its core businesses, Mercedes-Benz USA, LLC (MBUSA) has entered into a…
- 10151924Jul 2, 2018Liftgate intermittently does not open fully
Body and structure: other model years
| Year | Complaints | Share of year |
|---|---|---|
| 2017 | 1 | 14% |
| 2016 | 7 | 14% |
| 2015 | 4 | 13% |
| 2014 | 25 | 9% |
| 2013 | 18 | 11% |
| 2012 | 8 | 4% |
| 2011 | 15 | 7% |
| 2010 | 11 | 6% |
| 2009 | 3 | 5% |
| 2008 | 6 | 3% |
| 2007 | 2 | 1% |
| 2006 | 5 | 1% |
| 2005 | 1 | 7% |
Other parts of the 2010 Mercedes-Benz E350
68 complaintsFuel system
20 complaintsOther or unknown
19 complaintsElectrical system
17 complaintsSuspension
17 complaintsEngine
15 complaintsBrakes
14 complaintsTransmission and drivetrain
14 complaintsSteering
8 complaintsExterior lighting
5 complaintsSeats
4 complaintsVehicle speed control
4 complaints
← All problems reported for the 2010 Mercedes-Benz E350
About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.
To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology