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Body and structurePart report

2006 Mercedes-Benz E350 Body and structure Problems

Complaints
5about this part
Share
1%of 400 total for the year
Median mileage
85,000miles
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 5 complaints about the body and structure of the 2006 Mercedes-Benz E350, 1% of the 400 complaints for this model year. Where a mileage was given, the median is 85,000 miles. 1 of these say a crash was involved, according to the filers.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“I am reporting a very serious, disturbing, shocking and tragic accident on 9/12/2015 on randall road in elgin, il USA at 2:35 pm just after big timber road signal.my southbound 2006 mercedes benz E350 car was hit by the high speed out of control northbound 2014 toyota corolla, which had crossed/swerved the center line and resulted in a head on collision/crash.....updated 10-27-15”

NHTSA complaint #10779783, filed 2015-10, 117,000 miles

“The same day plate light, trunk remote opener stop working due to melted brown wire in the trunk dealer do not want to fix actually asked for 300 to check the problem . A lots of discussion is going on the web to solve but I could not . Fuel smell in the garage often.”

NHTSA complaint #10535840, filed 2013-08, 85,000 miles

“Received recall notice stating seal of sun roof might fail and cause it to come loose while driving. Dealership states part needed is not available and no information available about when it might be.”

NHTSA complaint #11318602, filed 2020-03

Related service bulletins

Body and structure: other model years

YearComplaintsShare of year
2017114%
2016714%
2015413%
2014259%
20131811%
201284%
2011157%
2010116%
200935%
200863%
200721%
200651%
200517%

Other parts of the 2006 Mercedes-Benz E350

Fuel system
219 complaints
Brakes
54 complaints
Engine
50 complaints
Transmission and drivetrain
37 complaints
Engine cooling
22 complaints
Electrical system
19 complaints
Air bags
13 complaints
Other or unknown
11 complaints
Visibility (wipers, defrost, mirrors)
8 complaints
Vehicle speed control
7 complaints
Steering
6 complaints
Electronic stability control
5 complaints

← All problems reported for the 2006 Mercedes-Benz E350

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology