2021 Mercedes-Benz E350 Transmission and drivetrain Problems
- Complaints
- 3about this part
- Share
- 23%of 13 total for the year
- Median mileage
- —not reported
- Trend
- Not enough dataFewer than 15 complaints, too few for a reliable trend.
NHTSA recorded 3 complaints about the transmission and drivetrain of the 2021 Mercedes-Benz E350, 23% of the 13 complaints for this model year.
Fewer than 15 complaints name this part, so treat the figures as a rough indication only.
Example complaints
Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.
“The Mercedes E350, with 22,000 miles suffered a catastrophic transmission failure while driving on the highway. I managed to exit the highway but the car could not be moved and left me stranded.”
NHTSA complaint #11672435, filed 2025-07“With the car only have about 15,000 miles the transmission has failed . I have seen there have been recalls of other models with similar complaints of transmission failure .”
NHTSA complaint #11708688, filed 2026-01Related service bulletins
- 11038187Sep 26, 2026Complaint Customer complaints relating to automatic transmission 725.0 (NAG3 Classic /9G‑TRONIC automatic transmission) and 725.1 (NAG3 facelift/9G‑TRONIC automatic transmission…
- 11037987Sep 14, 2026Complaint Only vehicles with a variable transfer case are affected. This can be identified through control unit N45 or N15/7 in the quick test. When accelerating with light load…
- 11037616Sep 4, 2026Complaint Customer complaints relating to automatic transmission 725.0 (NAG3 Classic / 9G‑TRONIC automatic transmission) and 725.1 (NAG3 facelift/9G‑TRONIC automatic transmission…
- 11036077Aug 5, 2026Complaint This document is intended as a pre-case diagnostic reference for transmission related concerns. It will also ensure that if a case is necessary, all supporting…
- 11035780Aug 4, 2026Complaint Mercedes-Benz USA is currently experiencing limited availability of transmission fluid specification ATF 236.17 due to a global supply constraint. 236.17 ATF 1L and 5L…
- 11035005Jul 14, 2026Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The noise is heard once in each instance when changing direction of…
- 11033050May 22, 2026Dear Mercedes-Benz USA Dealers, The part numbers listed in the chart below should no longer be installed, and any existing stock must be returned to your facing PDC. The deadline…
- 11032736May 15, 2026The part numbers listed in the chart below should no longer be installed, and any existing stock must be returned to your facing PDC. The deadline for all dealer returns is no…
- 11028834Feb 13, 2026Complaint Check engine light on with the following fault is current in the VGS Control Unit: P084300 Oil pressure sensor 'A' has a short circuit to positive stored in VGS control…
- 11028813Feb 12, 2026Complaint The vehicle cannot disengage “P” (Park), and a red warning message appears in the instrument cluster. Cause Only vehicles with transmission NAG3C 725.0 and engine M264…
Transmission and drivetrain: other model years
| Year | Complaints | Share of year |
|---|---|---|
| 2022 | 1 | 11% |
| 2021 | 3 | 23% |
| 2020 | 1 | 13% |
| 2016 | 5 | 10% |
| 2015 | 1 | 3% |
| 2014 | 15 | 5% |
| 2013 | 7 | 4% |
| 2012 | 10 | 5% |
| 2011 | 6 | 3% |
| 2010 | 14 | 8% |
| 2009 | 2 | 3% |
| 2008 | 5 | 3% |
| 2007 | 21 | 6% |
| 2006 | 37 | 9% |
| 2003 | 1 | 14% |
Other parts of the 2021 Mercedes-Benz E350
4 complaintsEngine
4 complaintsBack-over prevention (rear camera)
3 complaintsFuel system
3 complaintsBrakes
1 complaints
← All problems reported for the 2021 Mercedes-Benz E350
About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.
To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology