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Other or unknownPart report

2022 Mercedes-Benz E350 Other or unknown Problems

Complaints
3about this part
Share
33%of 9 total for the year
Median mileage
—not reported
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 3 complaints about the other or unknown of the 2022 Mercedes-Benz E350, 33% of the 9 complaints for this model year.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“The panoramic sunroof exploded while inside the car without warning. Contacted the dealership/service center on Friday 9/15/2023, was told they have not received a memo regarding the panoramic sunroofs in the 2022 E350, however; this is a know problem. I was told that this is not covered of my warranty because they assume something had to hit the glass, provided evidence via my security camera that not fell and hit the glass. Even after this happened the warning system did not even go off to indicate there was a problem.”

NHTSA complaint #11545429, filed 2023-09

“On June 16, 2024, while driving my 2022 Mercedes E 350 with my two young children in the car, my sunroof suddenly and literally exploded. Fortunately, the sunroof screen was closed, which prevented us from sustaining any direct injuries. However, the entire sunroof shattered and is now gone. The explosion sounded like a gunshot, causing immediate and extreme distress. My body began shaking uncontrollably from the shock and fear of the incident. This unexpected event posed a severe safety hazard, and I am deeply concerned about the potential risks to other drivers with similar vehicles. …”

NHTSA complaint #11595117, filed 2024-06

Related service bulletins

Other or unknown: other model years

YearComplaintsShare of year
2024120%
2023350%
2022333%
2020338%
2017343%
2016816%
2015310%
20142710%
20131610%
2012178%
2011188%
20101910%
200912%
200874%
200762%
2006113%
200517%

Other parts of the 2022 Mercedes-Benz E350

Forward collision avoidance
3 complaints
Electrical system
1 complaints
Fuel system
1 complaints
Transmission and drivetrain
1 complaints
Vehicle speed control
1 complaints
Visibility (wipers, defrost, mirrors)
1 complaints

← All problems reported for the 2022 Mercedes-Benz E350

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 31, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology