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EnginePart report

2021 Mercedes-Benz S 580 Engine Problems

Complaints
4about this part
Share
12%of 34 total for the year
Median mileage
—not reported
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 4 complaints about the engine of the 2021 Mercedes-Benz S 580, 12% of the 34 complaints for this model year.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“The vehicle lost acceleration and the check engine light came on. I took the vehicle to Mercedes dealership. They quoted that the Camtronic actuator has failed and needs to be replaced. Cost $9000. I have now seen online a recall for 2021 mercedes s580's for CAMTRONIC actuator failure issue. However- my VIN is not included in the recall. Please advise what I should do.”

NHTSA complaint #11736544, filed 2026-05

“Background: This is a V-8, gas vehicle.The 12-volt battery gives CRITICAL CHARGE notifications constantly. Incident: Dry pavement, 400-mile, January winter night, highway driving in Wisconsin Northwoods at posted 70 mph; some with cruise control, some without cruise control. Seat belt was in use. On four occasions, car independently, without any warning, dropped from 70 mph to 35 mph, projecting me forward. No reduction in speed signage No small town drive through. With car and semi-truck traffic behind me, luckily no rear end collisions, injury or death occurred. …”

NHTSA complaint #11449057, filed 2022-01

“Engine oil pressure control valve (Component Y130 / Diagnostic Code P06DA) and internal submerged wiring harness failed at 44,022 miles, triggering a Check Engine Light and causing an immediate failure during Massachusetts state OBD-II emissions inspections. Mercedes-Benz quoted over $16,500 to perform an engine-out repair to fix this internal component flaw. The internal harness sits in hot engine oil and degrades over time, creating an ongoing defect”

NHTSA complaint #11771797, filed 2026-10

Related service bulletins

Engine: other model years

YearComplaintsShare of year
2021412%

Other parts of the 2021 Mercedes-Benz S 580

Electrical system
10 complaints
Other or unknown
6 complaints
Wheels
6 complaints
Forward collision avoidance
5 complaints
Engine cooling
4 complaints
Brakes
3 complaints
Lane departure
3 complaints
Vehicle speed control
3 complaints
Exterior lighting
2 complaints
Fuel system
2 complaints
Tires
2 complaints
Transmission and drivetrain
2 complaints

← All problems reported for the 2021 Mercedes-Benz S 580

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 30, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology