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Mercedes-Benz S 580Model year report

2021 Mercedes-Benz S 580 Problems

Complaints
34filed with NHTSA
Median mileage
2,097miles, 8 complaints with mileage
Recalls
16campaigns on record
Trend
StableComplaints filed in the last 3 full calendar years are within 25% of the 3 years before.
NHTSA crash rating
—no overall rating published
EPA fuel economy
20 mpgcombined, 4.0L 8-cyl · hybrid 4WD · 17 city / 25 hwy

Sources: NHTSA records for the 2021 Mercedes-Benz S 580 (complaints, recalls, investigations), EPA fuel economy. Report an error

NHTSA recorded 34 consumer complaints for the 2021 Mercedes-Benz S 580. The part named most often is electrical system, with 10 complaints (29% of the total), followed by other or unknown (6) and wheels (6). 8 of the complaints include a mileage, and 100% of those were filed for vehicles with under 50,000 miles; the median is 2,097 miles. Of all complaints, 2 involved a crash, 3 an injury, 1 a death, according to the filers. NHTSA lists 16 recall campaigns and 310 technical service bulletins for this model year. Electrical system complaints overlap with 2 recall campaigns and 162 technical service bulletins filed under the same part. Other or unknown complaints overlap with 10 technical service bulletins filed under the same part.

Not compared (fewer than 3 comparable model years). Model years 2008–2023 of the same vehicle that have at least 25 complaints are compared, and a model needs at least 3 of them.

Which parts are reported most

Complaints can name more than one part, so the counts add up to more than the total. Select a part to see its complaints, recalls and bulletins.

Also reported: Fuel system (2), Tires (2), Transmission and drivetrain (2), Visibility (wipers, defrost, mirrors) (2), Suspension (1).

Example complaints

Electrical system: “Driving on highway at about 50 mph when the brakes suddenly slammed on and brought car to a sudden, near stop. The stop was so sudden our seatbelts engaged and we thought we were struck in the rear by another car. Electrical module issues that cause battery to drain while vehicle is turned off have been ongoing since I purchased the car in October, 2021. Car has been in for service related to this problem 6 times and for over 60 days.”

NHTSA complaint #11501439, filed 2023-01

Other or unknown: “Car was in for recall Dec 7,2025 to Mercedes Benz of Rockville Centre service 110 Graham Avenue Hempstead Ny they are having difficulties with the recall it is now Dec 30, 2025 still not repaired they told me it was a parts problem they ordered parts twice now they are saying it might be a software problem they are not sure they do not know when i will get my vehicle back they dont even know the reason why its not taking the recall”

NHTSA complaint #11708011, filed 2025-12

Wheels: “I have had one tire blow out after traveling over a moderate pot hole, and 3 other tires that have been damaged with bubbles due to excessive stress from normal driving. In addition to the damaged tires, I have had 3 bent wheels all due to normal driving because the 21 inch wheels/tires on this vehicle cannot tolerate the loads during normal driving. This is a well-known defect by Mercedes and I believe it is a design defect and that it is dangerous.”

NHTSA complaint #11526539, filed 2023-06

Forward collision avoidance: “While on the freeway, going approximately 70 mph, the vehicles onboard cameras all failed and I got a warning that said “camera dirty/unavailable/traffic sign assist currently unavailable”. Because of this failure, I almost crashed the car in Front of me. I cleaned all the cameras. The message continues to appear. The dealer said “it’s a known malfunction with this particular model, based on the chip shortage, during Covid”. My car has 57000 miles and apparently several owners of this model, are experiencing the same issue. …”

NHTSA complaint #11636844, filed 2025-01

Mileage when problems were reported

100% of the 8 complaints with a mileage were filed for vehicles with under 50,000 miles; the middle half falls between 1,000 and 20,000 miles.

63%0–1025%10–2513%25–500%50–750%75–1000%100–1500%150+
Share of complaints by mileage when the problem was reported, in thousands of miles (8 complaints with mileage). Red bars: under 50,000 miles. Bucket widths differ. Median: 2,097 miles.

Complaints by year filed

Trend: stable. Complaints filed in the last 3 full calendar years are within 25% of the 3 years before.

20212022720232024202572026
Complaints by year the complaint was filed with NHTSA. Red bars: the last 3 full calendar years used for the trend. The current year (2026) is partial.

Fuel economy and running cost

EPA ratings for each 2021 Mercedes-Benz S 580 version. Annual fuel cost is the EPA's estimate at its current fuel prices for 15,000 miles a year (55% city driving).

VersionEngineTransmissionCityHwyComb.Fuel / yr
S580 4matic 4WD4.0L 8-cyl · hybrid9-speed automatic172520$4,100
S580 4matic Maybach 4WD4.0L 8-cyl · hybrid9-speed automatic162419$4,350

Source: U.S. EPA and Department of Energy, fueleconomy.gov. Ratings are for comparing vehicles; real-world mileage varies with driving and conditions.

Recalls and investigations

See all 16 recalls for the 2021 Mercedes-Benz S 580 → · Check a VIN at nhtsa.gov/recalls

Technical service bulletins

TSBs are manufacturer notes to dealers about known repair procedures. They are not recalls and do not by themselves mean a vehicle has a fault. 310 on record; the latest 10 are shown.

See all 310 bulletins →

Other model years of the Mercedes-Benz S 580

YearComplaintsMedian miRecallsCrash ★MPGScore (50 = typical)Trend
202364,0007———Too new
2021342,09716—20Not compared (fewer than 3 comparable model years)Stable

All Mercedes-Benz S 580 model years

Frequently asked questions

How many NHTSA complaints does the 2021 Mercedes-Benz S 580 have?

NHTSA recorded 34 consumer complaints for the 2021 Mercedes-Benz S 580 as of Oct 27, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

What part of the 2021 Mercedes-Benz S 580 is reported most often?

Electrical system is named most often, in 10 complaints (29% of the total), followed by other or unknown with 6.

Has the 2021 Mercedes-Benz S 580 been recalled?

NHTSA lists 16 recall campaigns for this model year. To check a specific vehicle, enter its VIN at nhtsa.gov/recalls.

What gas mileage does the 2021 Mercedes-Benz S 580 get?

The EPA rates the 2021 Mercedes-Benz S 580 (S580 4matic, 4.0L 8-cyl · hybrid) at 20 mpg combined, 17 city and 25 highway, with an estimated annual fuel cost of $4,100 at 15,000 miles a year. Other engine and drive versions are rated differently.

At what mileage are problems with the 2021 Mercedes-Benz S 580 reported?

Among the 8 complaints that include a mileage, the median is 2,097 miles and the middle half falls between 1,000 and 20,000 miles; 100% were filed for vehicles with under 50,000 miles.

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Oct 27, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate. Fuel economy is from the EPA and DOE (fueleconomy.gov).

Complaint counts come from NHTSA’s public complaint database; we count each complaint once. The source records for this vehicle are on nhtsa.gov. Scores and trends are our own summaries of that data, described in the methodology. This page is not legal, safety or repair advice: for a specific vehicle, check its VIN at nhtsa.gov/recalls and ask a qualified mechanic. See an error? Tell us.