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TiresPart report

2021 Mercedes-Benz S 580 Tires Problems

Complaints
2about this part
Share
6%of 34 total for the year
Median mileage
3,000miles
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 2 complaints about the tires of the 2021 Mercedes-Benz S 580, 6% of the 34 complaints for this model year. Where a mileage was given, the median is 3,000 miles.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“I purchased this car as a certified pre-owned vehicle from Mercedes Benz in December 2024 with 14,000 miles on the odometer. This vehicle has factory 21-inch AMG rims. Since that time, I have had to replace 5 tires on this vehicle, all from Mercedes Benz dealerships. I purchased an additional $2,000 tire insurance policy from Mercedes Benz due to this recurrent issue. Due to the size of this rim, these tires are extremely prone to blowing and flats. Furthermore, this vehicle does not come with a spare tire or even with a storage compartment which can accommodate a spare tire. …”

NHTSA complaint #11646497, filed 2025-03

“The contact owns a 2021 Mercedes-Benz S580 equipped with Pirelli tires, Tire Line: P Zero MO-S, Tire Size: P255/35/R21 (Front tires) and P285/30/R21 (Rear Tires), DOT Number: (Unavailable). The contact stated while driving 30 MPH, the drove over a pothole and the driver’s side front tire experienced a blowout. The vehicle was towed to the dealer, and the contact was informed that there was a bubble on the side shoulder of the tire, and the tire needed to be replaced. The tire was replaced. …”

NHTSA complaint #11476303, filed 2022-07, 3,000 miles

Tires: other model years

YearComplaintsShare of year
2023350%
202126%

Other parts of the 2021 Mercedes-Benz S 580

Electrical system
10 complaintsOther or unknown
6 complaintsWheels
6 complaintsForward collision avoidance
5 complaintsEngine
4 complaintsEngine cooling
4 complaintsBrakes
3 complaintsLane departure
3 complaintsVehicle speed control
3 complaintsExterior lighting
2 complaintsFuel system
2 complaintsTransmission and drivetrain
2 complaints

← All problems reported for the 2021 Mercedes-Benz S 580

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Nov 1, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology