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Transmission and drivetrainPart report

2021 Mercedes-Benz S 580 Transmission and drivetrain Problems

Complaints
2about this part
Share
6%of 34 total for the year
Median mileage
976miles
Trend
Not enough dataFewer than 15 complaints, too few for a reliable trend.

NHTSA recorded 2 complaints about the transmission and drivetrain of the 2021 Mercedes-Benz S 580, 6% of the 34 complaints for this model year. Where a mileage was given, the median is 976 miles. 1 of these say a crash was involved, according to the filers.

Fewer than 15 complaints name this part, so treat the figures as a rough indication only.

Example complaints

Selected from NHTSA records; personal details are removed. They are consumer reports, not findings.

“The contact owns a 2021 Mercedes-Benz S580. The contact stated while driving at 60 MPH, the contact pressed a button on the steering wheel to engage the cruise control function on the vehicle. The contact stated when driving past a mileage sign stating 40 MPH, the vehicle suddenly reduce in speed to 40 MPH, while the contact was on the highway in the fast lane. The contact was able to move the vehicle over to the side of the road waited a few minutes took off the cruise control function and reapplied it back on and continued to drive the vehicle again. …”

NHTSA complaint #11442018, filed 2021-11, 976 miles

“Issue: STARTER BATTERY Repetitive online and dashboard screen message notices stating, BATTERY CHARGE Status Critical, at all hours of day and night requesting immediate 30-60-min. of driving or car will not start. Have had to wake up from nightime sleep to drive car in middle of night so it would start the next morning to drive to work. Also, multiple electrical problems related to this issue ensue. Unreliable vehicle start up; too great a demand on electrical system. Vehicle taken in to dealer for service five times in six months since new purchase. …”

NHTSA complaint #11449211, filed 2022-01

Related service bulletins

Transmission and drivetrain: other model years

YearComplaintsShare of year
202126%

Other parts of the 2021 Mercedes-Benz S 580

Electrical system
10 complaintsOther or unknown
6 complaintsWheels
6 complaintsForward collision avoidance
5 complaintsEngine
4 complaintsEngine cooling
4 complaintsBrakes
3 complaintsLane departure
3 complaintsVehicle speed control
3 complaintsExterior lighting
2 complaintsFuel system
2 complaintsTires
2 complaints

← All problems reported for the 2021 Mercedes-Benz S 580

About this data. Data from NHTSA (ODI) complaints, recalls, TSBs and investigations, updated Nov 1, 2026. Complaints are unverified consumer reports and may be duplicated or inaccurate.

To check a specific vehicle for open recalls, use its VIN at nhtsa.gov/recalls. Methodology